Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754002 | 0.92 | ALOX5 (0.47) | ALOX5PTGS2MEN1KMT2A | |
| SCHEMBL9754150 | 0.86 | ALOX5 (0.48) | ALOX5PTGS2KMT2A | |
| SCHEMBL9754099 | 0.82 | MAPT (0.45) | MEN1KMT2A | |
| SCHEMBL9630571 | 0.77 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9754000 | 0.76 | ALOX5 (0.46) | ALOX5PTGS2 | |
| SCHEMBL9754025 | 0.74 | ALOX5 (0.43) | ALOX5PTGS2 | |
| SCHEMBL9803529 | 0.73 | ALOX5 (0.43) | ALOX5PTGS2 | |
| SCHEMBL6547318 | 0.69 | SIGMAR1 (0.54) | SIGMAR1MEN1KMT2A | |
| SCHEMBL9754402 | 0.68 | ALOX5 (0.56) | ALOX5PTGS2MEN1KMT2A | |
| Isobutylbenzene SCHEMBL363626 | 0.67 | TAAR1 (0.61) | ALOX5PTGS2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008744-A1 | THIAZOLE LIPOXYGENASE-INHIBITING COMPOUNDS DERIVED FROM NON-STEROIDAL ANTIINFLAMMATORY CARBOXYLIC ACIDS | ABBOTT LABORATORIES (US) | 1991-06-27 | — | — | WO | disclosed |