Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | IL2 | P60568 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754434 | 0.74 | IL2 (0.46) | PGRIL2 | |
| Iodide SCHEMBL10742181 | 0.73 | PTPN11 (0.32) | — | |
| SCHEMBL16689869 | 0.66 | ACHE (0.46) | PDK2 | |
| SCHEMBL9754458 | 0.61 | PDK2 (0.35) | PGRPDK2 | |
| SCHEMBL1884446 | 0.59 | CRHR1 (0.36) | PDK2 | |
| SCHEMBL22833917 | 0.59 | ALDH1A1 (0.46) | — | |
| SCHEMBL3750200 | 0.58 | CRHR1 (0.37) | PDK2 | |
| SCHEMBL15846774 | 0.58 | PDK2 (0.37) | PDK2 | |
| SCHEMBL16050969 | 0.57 | CRHR1 (0.39) | PDK2 | |
| SCHEMBL16219593 | 0.57 | RAPGEF4 (0.40) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013065-A1 | 6-ARYL-2-SUBSTITUTED BENZOIC ACID HERBICIDES | FMC CORPORATION (US) | 1991-09-05 | — | — | WO | disclosed |