Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | CETP | P11597 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671054 | 0.88 | ALDH1A1 (0.46) | HSD17B10HRH1USP2SMN1; SMN2TDP1 | |
| SCHEMBL9756680 | 0.81 | MEN1 (0.55) | HSD17B10SMN1; SMN2GBA1MEN1MAPT | |
| SCHEMBL9669903 | 0.77 | HRH1 (0.53) | HRH1USP2SMN1; SMN2TDP1PDE4A | |
| SCHEMBL9756683 | 0.72 | CASP1 (0.43) | USP2SMN1; SMN2CASP1CASP4CASP5 | |
| SCHEMBL9756677 | 0.70 | KMT2A (0.47) | SMN1; SMN2GBA1MEN1CYP2C19KMT2A | |
| SCHEMBL9756685 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2TDP1GBA1ALDH1A1MEN1 | |
| SCHEMBL9756638 | 0.69 | GBA1 (0.49) | GBA1MEN1KMT2A | |
| SCHEMBL8542091 | 0.68 | HRH1 (1.00) | HRH1USP2SMN1; SMN2TDP1PDE4A | |
| SCHEMBL11215614 | 0.68 | HTR3E (0.58) | HRH1USP2SMN1; SMN2TDP1CETP | |
| SCHEMBL778188 | 0.67 | SMN1; SMN2 (1.00) | HRH1USP2SMN1; SMN2TDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | claimed |