Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756894 | 0.74 | TAS1R3 (0.45) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL9756976 | 0.73 | JUN (0.49) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL12892199 | 0.71 | PYGL (0.53) | RAB9ANPC1MAPTKMT2ALMNA | |
| SCHEMBL9756825 | 0.71 | DAO (0.51) | ALDH1A1RAB9AMAPTKMT2ALMNA | |
| SCHEMBL9756823 | 0.71 | DAO (0.51) | ALDH1A1RAB9AMAPTKMT2ALMNA | |
| SCHEMBL9560160 | 0.70 | RAB9A (0.60) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL9756888 | 0.69 | NAMPT (0.55) | RAB9ANPC1MAPTKDM4EMAPK1 | |
| SCHEMBL9756826 | 0.69 | RAB9A (0.60) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL9756846 | 0.68 | NPC1 (0.42) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL9756847 | 0.68 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |