Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303832 | 0.86 | DRD4 (0.39) | DRD2HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL7990198 | 0.84 | HTR1A (0.63) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL8302484 | 0.82 | PARP1 (0.47) | PARP1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL7997114 | 0.82 | HTR1A (0.60) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL8302001 | 0.80 | PARP1 (0.48) | PARP1DRD2DRD3 | |
| SCHEMBL8446873 | 0.77 | DRD2 (0.45) | PARP1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL9760169 | 0.76 | HTR2A (0.52) | PARP1DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL8302387 | 0.76 | PARP1 (0.47) | PARP1 | |
| SCHEMBL8301654 | 0.75 | PARP1 (0.46) | PARP1 | |
| SCHEMBL8306648 | 0.74 | DRD4 (0.54) | PARP1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041445-A | Antipsychotic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-08-20 | — | — | US | claimed |