Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762150 | 0.75 | KMT2A (0.48) | KMT2ASMN1; SMN2MAPTL3MBTL1ATM | |
| SCHEMBL9761085 | 0.72 | MAPT (0.40) | KMT2AMAPTL3MBTL1ATMLMNA | |
| SCHEMBL9761689 | 0.72 | KCNH2 (0.36) | MAPTALDH1A1 | |
| SCHEMBL9761357 | 0.68 | HPGD (0.37) | KMT2ASMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL9761212 | 0.67 | PARP1 (0.36) | KMT2ASMN1; SMN2MAPTL3MBTL1LMNA | |
| SCHEMBL9762357 | 0.62 | L3MBTL1 (0.35) | KMT2ASMN1; SMN2MAPTL3MBTL1ATM | |
| SCHEMBL9761839 | 0.62 | KMT2A (0.46) | KMT2AMAPTL3MBTL1ATMHTT | |
| SCHEMBL9761709 | 0.62 | KMT2A (0.39) | KMT2AMAPTL3MBTL1LMNAHTT | |
| SCHEMBL9761852 | 0.62 | L3MBTL1 (0.41) | KMT2ASMN1; SMN2MAPTL3MBTL1ATM | |
| SCHEMBL9762508 | 0.62 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |