Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307238 | 0.88 | AOC3 (0.38) | ACHEAOC3SIGMAR1HSD17B1HSD17B2 | |
| SCHEMBL11590656 | 0.84 | RAB9A (0.39) | HSD17B1HSD17B2ALDH1A1LMNACYP3A4 | |
| SCHEMBL3440717 | 0.79 | ACHE (0.48) | ACHESIGMAR1HSD17B1HSD17B2TP53 | |
| SCHEMBL9762958 | 0.79 | HTR3E (0.42) | AOC3EGFRCSF1RTP53ALDH1A1 | |
| SCHEMBL10350090 | 0.79 | ALDH1A1 (0.42) | SIGMAR1TDP1TP53ALDH1A1LMNA | |
| SCHEMBL11321042 | 0.79 | MAPT (0.43) | ACHEAOC3TDP1TP53ALDH1A1 | |
| SCHEMBL10531957 | 0.78 | LMNA (0.45) | HSD17B1HSD17B2TP53ALDH1A1MAPK1 | |
| SCHEMBL8652899 | 0.77 | CA4 (0.35) | TDP1TP53ALDH1A1LMNA | |
| SCHEMBL11214478 | 0.76 | HSD17B1 (0.40) | HSD17B1HSD17B2TP53LMNAMAPT | |
| SCHEMBL1288272 | 0.76 | ACHE (0.44) | ACHESIGMAR1HSD17B1HSD17B2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997918-A | Benzthiazolium azo dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0105031-A2 | Cationic azo dyestuffs | CIBA-GEIGY AG (CH) | 1984-04-04 | — | — | EP | disclosed |