Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | USP8 | P40818 | 2/20 | 0.39 |
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490 | 0.92 | S100A4 (0.57) | HSP90AA1S100A4PTPN1PPOXKDM4E | |
| SCHEMBL8773066 | 0.80 | S100A4 (0.56) | HSP90AA1S100A4PTPN1PPOXPTPN11 | |
| SCHEMBL5811756 | 0.80 | ESR2 (0.61) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL30004162 | 0.80 | ESR2 (0.61) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL18992102 | 0.78 | KDM4E (0.38) | HSP90AA1S100A4KDM4EALDH1A1CYP3A4 | |
| SCHEMBL30003252 | 0.78 | KDM4E (0.38) | HSP90AA1S100A4KDM4EALDH1A1CYP3A4 | |
| SCHEMBL25379798 | 0.77 | ALDH1A1 (0.52) | S100A4PTPN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9389370 | 0.77 | BCL2 (0.58) | S100A4KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL22785955 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL9627970 | 0.77 | ALDH1A1 (0.57) | HSP90AA1S100A4PTPN1PPOXKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534436-B1 | Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel | SHINETSU CHEMICAL CO (JP) | 1996-08-14 | — | — | EP | claimed |
| US-5411675-A | Mixtures of aromatic diamines, hydroxynaphthoquinone, acid and silica sol as antiscaling agents | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | claimed |
| EP-0534436-A1 | Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel | Shin-Etsu Chemical Co., Ltd. (JP) | 1993-03-31 | — | — | EP | claimed |
| EP-0007985-B1 | 6-CHLORO-2,3-DIHYDROXY-1,4-NAPHTHOQUINONE AND ITS 2,3-DIESTERS, AND THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1982-09-01 | — | — | EP | claimed |
| EP-0007985-A1 | 6-Chloro-2,3-dihydroxy-1,4-naphthoquinone and its 2,3-diesters, and their preparation | SYNTEX (U.S.A.) INC. (US) | 1980-02-20 | — | — | EP | claimed |
| JP-5194608-A | — | — | None | — | — | JP | disclosed |
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2023-03-28 | — | — | US | disclosed |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| US-10829427-B2 | Naphthoquinones, pro-drugs, and methods of use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-11-10 | — | — | US | disclosed |
| US-10829427-B2 | Naphthoquinones, pro-drugs, and methods of use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190071380-A1 | NAPHTHOQUINONES, PRO-DRUGS, AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-03-07 | — | — | US | disclosed |
| US-20190071380-A1 | NAPHTHOQUINONES, PRO-DRUGS, AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-03-07 | — | — | US | disclosed |
| EP-0517876-A1 | THERAPEUTIC BENZAZEPINE COMPOUNDS. | ICI PLC (GB) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992011854-A1 | THERAPEUTIC BENZAZEPINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-23 | — | — | WO | disclosed |
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |
| EP-0007985-B1 | 6-CHLORO-2,3-DIHYDROXY-1,4-NAPHTHOQUINONE AND ITS 2,3-DIESTERS, AND THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4255405-A | 2,3-DIESTERS | SYNTEX (U.S.A.) INC. (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0007985-A1 | 6-Chloro-2,3-dihydroxy-1,4-naphthoquinone and its 2,3-diesters, and their preparation | SYNTEX (U.S.A.) INC. (US) | 1980-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829427-B2 | Naphthoquinones, pro-drugs, and methods of use thereof | NQO1, RECQL, ABCB1 | HSP90AA1 1460/4885S100A4 2683/4885PTPN1 4468/4885 |
| US-20190071380-A1 | NAPHTHOQUINONES, PRO-DRUGS, AND METHODS OF USE THEREOF | NQO1, RECQL, ABCB1 | HSP90AA1 1460/4885S100A4 2683/4885PTPN1 4468/4885 |
| US-11613509-B2 | Radical polymerization control agent and radical polymerization control method | PPOX, NOX4, CROCC | HSP90AA1 2180/4885S100A4 1775/4885PTPN1 1787/4885 |
| US-20210122692-A1 | RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD | PPOX, NOX4, CROCC | HSP90AA1 2180/4885S100A4 1775/4885PTPN1 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.