Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488186 | 0.96 | AR (0.52) | ARHPGDALDH1A1SIGMAR1LMNA | |
| SCHEMBL10477677 | 0.96 | AR (0.52) | ARHPGDALDH1A1SIGMAR1LMNA | |
| SCHEMBL9763021 | 0.86 | AR (0.51) | ARHPGDALDH1A1SIGMAR1LMNA | |
| SCHEMBL9763725 | 0.86 | DRD2 (0.51) | ARHPGDALDH1A1SIGMAR1LMNA | |
| SCHEMBL9762652 | 0.79 | POLB (0.51) | ALDH1A1CNR1CNR2S1PR1S1PR3 | |
| SCHEMBL10477755 | 0.79 | SIGMAR1 (0.69) | SIGMAR1MAOACHRM2BCHE | |
| SCHEMBL9764394 | 0.79 | SIGMAR1 (0.69) | SIGMAR1MAOACHRM2BCHE | |
| SCHEMBL9762627 | 0.79 | SIGMAR1 (0.52) | ARHPGDSIGMAR1CNR1CNR2 | |
| SCHEMBL9763280 | 0.78 | SIGMAR1 (0.55) | ARALDH1A1SIGMAR1MAOAADRB1 | |
| Benzene SCHEMBL27952372 | 0.78 | MAOA (0.65) | HPGDALDH1A1SIGMAR1LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |