Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143982 | 0.89 | PTGS2 (0.57) | PTGS2LTA4HPDE10AKDM4EHRH3 | |
| SCHEMBL3242252 | 0.83 | LTA4H (0.42) | PTGS2LTA4HPDE10AKDM4ELMNA | |
| SCHEMBL147539 | 0.83 | LOXL2 (0.52) | PTGS2LTA4HPDE10AKDM4ETLR4 | |
| SCHEMBL29610302 | 0.83 | LOXL2 (0.52) | PTGS2LTA4HPDE10AKDM4ETLR4 | |
| SCHEMBL8510667 | 0.81 | LTA4H (0.50) | PTGS2LTA4HPDE10AKDM4ETLR4 | |
| SCHEMBL5443693 | 0.81 | LTA4H (0.50) | PTGS2LTA4HPDE10AKDM4ETLR4 | |
| SCHEMBL5686657 | 0.80 | LTA4H (0.54) | PTGS2LTA4HPDE10AKDM4EHRH3 | |
| SCHEMBL3985514 | 0.80 | L3MBTL1 (0.54) | PTGS2LTA4HPDE10AKDM4EMAPK1 | |
| SCHEMBL10753672 | 0.80 | PTGS2 (0.50) | PTGS2LTA4HPDE10AKDM4EHRH3 | |
| SCHEMBL568653 | 0.80 | LTA4H (0.50) | PTGS2LTA4HPDE10AKDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5064846-A | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| US-4992453-A | Certain thioimidate and amidine insecticides | ICI AMERICAS INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4931448-A | Thiomidate insecticides | ICI AMERICAS INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0317266-A2 | Novel thioimidate and amidine insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |