Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763777 | 0.81 | SIGMAR1 (0.49) | SIGMAR1MAOACHRM2DPP7NPC1 | |
| SCHEMBL9763258 | 0.80 | SIGMAR1 (0.50) | SIGMAR1MAOACHRM2DPP7NPC1 | |
| SCHEMBL10465458 | 0.79 | HRH3 (0.43) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9764397 | 0.78 | ACACB (0.43) | RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL9763136 | 0.78 | DRD4 (0.47) | MAOACHRM2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9763675 | 0.77 | HRH3 (0.41) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL10465318 | 0.76 | HRH3 (0.40) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9763494 | 0.75 | DRD2 (0.47) | SIGMAR1MAOADRD2CHRM2NPC1 | |
| SCHEMBL9764480 | 0.74 | MMP2 (0.43) | SIGMAR1MAOACHRM2 | |
| SCHEMBL16812990 | 0.74 | CHRM2 (0.50) | SIGMAR1MAOACHRM2DPP7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |