Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763258 | 0.99 | SIGMAR1 (0.50) | SIGMAR1MAOACHRM2HRH3BCHE | |
| SCHEMBL9764527 | 0.90 | SIGMAR1 (0.48) | SIGMAR1MAOACHRM2BCHENPC1 | |
| SCHEMBL10477755 | 0.83 | SIGMAR1 (0.69) | SIGMAR1MAOACHRM2BCHEMAPT | |
| SCHEMBL9764394 | 0.83 | SIGMAR1 (0.69) | SIGMAR1MAOACHRM2BCHEMAPT | |
| SCHEMBL9763519 | 0.83 | ADRB2 (0.39) | BCHENPC1SMN1; SMN2MAPTFFAR4 | |
| Hydrochloric Acid SCHEMBL9258435 | 0.82 | SIGMAR1 (0.67) | SIGMAR1MAOACHRM2BCHEMAPT | |
| SCHEMBL9763710 | 0.81 | SIGMAR1 (0.43) | SIGMAR1MAOACHRM2HRH3NPC1 | |
| SCHEMBL16812990 | 0.81 | CHRM2 (0.50) | SIGMAR1MAOACHRM2HRH3MAPT | |
| SCHEMBL17832850 | 0.79 | CXCR4 (0.49) | MAOACHRM2HRH3MAPTDPP7 | |
| SCHEMBL10464983 | 0.79 | CHRM2 (0.59) | SIGMAR1MAOACHRM2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |