Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764480 | 0.79 | MMP2 (0.43) | ACACBGAAALDH1A1LMNAMAPK1 | |
| SCHEMBL9763710 | 0.78 | SIGMAR1 (0.43) | HRH3SMN1; SMN2RAB9A | |
| SCHEMBL9763136 | 0.74 | DRD4 (0.47) | SMN1; SMN2GAALMNAMAPK1RAB9A | |
| SCHEMBL9764569 | 0.73 | SNCA (0.38) | ACACBHPGDGRM5HRH3GAA | |
| SCHEMBL9764451 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAALDH1A1LMNAMAPK1 | |
| SCHEMBL9763494 | 0.72 | DRD2 (0.47) | HPGDSMN1; SMN2RAB9A | |
| SCHEMBL3644126 | 0.71 | GRM5 (0.71) | ACACBHPGDGRM5SMN1; SMN2GAA | |
| SCHEMBL9764455 | 0.71 | MAOA (0.40) | GAAMAPK1 | |
| SCHEMBL9764499 | 0.71 | KDM4E (0.45) | GAAALDH1A1MAPK1 | |
| SCHEMBL20183883 | 0.69 | HPGD (0.59) | ACACBHPGDGRM5HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |