Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764455 | 0.84 | MAOA (0.40) | DRD2DRD3DRD4MAOACHRM2 | |
| SCHEMBL9763725 | 0.81 | DRD2 (0.51) | DRD2DRD3DRD4ADRB2ADRB1 | |
| SCHEMBL9763021 | 0.80 | AR (0.51) | ADRB2ADRB1ADRB3ARHPGD | |
| SCHEMBL9763303 | 0.80 | NPC1 (0.46) | DRD3NPC1RAB9AARHPGD | |
| SCHEMBL9764480 | 0.78 | MMP2 (0.43) | MAOACHRM2SIGMAR1BCHEACHE | |
| SCHEMBL9763136 | 0.78 | DRD4 (0.47) | DRD4NPC1RAB9ASMN1; SMN2MAOA | |
| SCHEMBL9764632 | 0.77 | DRD2 (0.47) | DRD2DRD3DRD4ADRB2ADRB1 | |
| SCHEMBL9764622 | 0.77 | DRD2 (0.47) | DRD2DRD3DRD4ADRB2ADRB1 | |
| SCHEMBL9764451 | 0.76 | SMN1; SMN2 (0.45) | NPC1SMN1; SMN2MAOABCHEACHE | |
| SCHEMBL9318691 | 0.75 | SLC2A1 (0.48) | MAOACHRM2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |