SCHEMBL134107

SCHEMBL134107

C=CCN(CCCO)C(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20274377 0.93 ALDH1A1 (0.39) ALDH1A1
SCHEMBL20287509 0.93 ALDH1A1 (0.39) ALDH1A1
SCHEMBL170399 0.89 ALDH1A1 (0.39) ALDH1A1
SCHEMBL24063928 0.86 CA12 (0.41) ALDH1A1
SCHEMBL14782153 0.85 NTRK2 (0.33)
SCHEMBL8942370 0.84 ZDHHC20 (0.43) ALDH1A1
SCHEMBL7132971 0.84 ALDH1A1 (0.40) ALDH1A1
SCHEMBL21387586 0.83 ZDHHC20 (0.45) ALDH1A1
SCHEMBL20274382 0.83 ZDHHC20 (0.45) ALDH1A1
SCHEMBL131046 0.82 ALDH1A1 (0.46) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11116702-B2 Dental composition DENTSPLY SIRONA INC. (US) 2021-09-14 US disclosed
US-10980713-B2 Dental composition DENTSPLY SIRONA INC. (US) 2021-04-20 US disclosed
US-20200022884-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2020-01-23 US disclosed
WO-2019173656-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-09-12 WO disclosed
US-20190274930-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-09-12 US disclosed
WO-2018108948-A1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2018-06-21 WO disclosed
EP-2611752-B1 DISPERSANT FOR GYPSUM PLASTER COMPOSITIONS SIKA TECH AG (CH) 2017-04-26 EP disclosed
US-8653161-B2 Dispersant for hydraulically setting systems SIKA TECHNOLOGY AG (CH) 2014-02-18 US disclosed
EP-2611752-A1 DISPERSANT FOR GYPSUM PLASTER COMPOSITIONS Sika Technology AG (CH) 2013-07-10 EP disclosed
US-8466244-B2 Dispersants for hydraulically setting systems SIKA TECHNOLOGY AG (CH) 2013-06-18 US disclosed
EP-2065350-B1 Dispersion aid for hydraulic setting systems SIKA TECHNOLOGY AG (CH) 2011-02-23 EP disclosed
EP-2065351-B1 Dispersing agent for hydraulically setting systems SIKA TECHNOLOGY AG (CH) 2011-01-26 EP disclosed
US-20100305238-A1 DISPERSANTS FOR HYDRAULICALLY SETTING SYSTEMS SIKA TECHNOLOGY AG (CH) 2010-12-02 US disclosed
US-20100137476-A1 DISPERSANT FOR PLASTER COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2010-06-03 US disclosed
WO-2010026085-A1 WATER-REDUCED HYDRAULICALLY CONSTRICTING COMPOSITIONS WITH TEMPORALLY EXTENDED FLOW CAPABILITY SIKA TECHNOLOGY AG (CH) 2010-03-11 WO disclosed
EP-2159203-A1 Additive for hydraulically setting systems with improved processing and low water reduction rate Sika Technology AG (CH) 2010-03-03 EP disclosed
EP-2154118-A1 Dispersing agent for gypsum compounds Sika Technology AG (CH) 2010-02-17 EP disclosed
EP-2065351-A1 Dispersing agent for hydraulically setting systems Sika Technology AG (CH) 2009-06-03 EP disclosed
EP-2065350-A1 Dispersion aid for hydraulic setting systems Sika Technology AG (CH) 2009-06-03 EP disclosed
EP-2006258-A1 Dispersant for gypsum compositions Sika Technology AG (CH) 2008-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190274930-A1 DENTAL COMPOSITION KATNAL2, PUF60, PGLS ALDH1A1 2727/4885
US-11116702-B2 Dental composition MTR, CAD, PAM ALDH1A1 1171/4885
US-20200022884-A1 DENTAL COMPOSITION MTR, CAD, PAM ALDH1A1 1171/4885
US-10980713-B2 Dental composition KATNAL2, PUF60, PGLS ALDH1A1 2727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.