SCHEMBL9764425

SCHEMBL9764425

CS(=O)(=O)Nc1ccc(CCOCCCCCCN(Cc2ccccc2)CC(O)c2cc(Cl)c(N)c(Cl)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.51
ADRB2 P07550 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9764429 0.88 ADRB2 (0.41) KCNH2ADRB2
SCHEMBL9764456 0.88 ADRB2 (0.41) KCNH2ADRB2
SCHEMBL9764542 0.88 ADRB2 (0.41) KCNH2ADRB2
SCHEMBL9764436 0.87 KCNH2 (0.44) KCNH2
SCHEMBL9764430 0.87 KCNH2 (0.44) KCNH2
SCHEMBL9764389 0.87 ADRB2 (0.39) KCNH2ADRB2
SCHEMBL9764694 0.85 NR1H3 (0.45) KCNH2ADRB2
SCHEMBL9764329 0.85 ADRB2 (0.39) ADRB2
SCHEMBL9764371 0.85 ADRB2 (0.41) KCNH2ADRB2
SCHEMBL9764242 0.83 MC4R (0.39) KCNH2ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006556-A Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction GLAXO GROUP LIMITED (GB) 1991-04-09 US disclosed
US-4943591-A TREATMENT OF ASTHMA AND BRONCHITIS GLAXO GROUP LIMITED (GB) 1990-07-24 US disclosed