Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764371 | 0.90 | ADRB2 (0.41) | NR1H3KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL9764429 | 0.86 | ADRB2 (0.41) | NR1H3KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL9764456 | 0.86 | ADRB2 (0.41) | NR1H3KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL9764301 | 0.85 | NR1H3 (0.45) | NR1H3ADRB2ALDH1A1BCHE | |
| SCHEMBL9764389 | 0.85 | ADRB2 (0.39) | NR1H3KDM4EADRB2SLC2A1BCHE | |
| SCHEMBL9321535 | 0.83 | MAOB (0.37) | NR1H3KDM4EADRB2BCHEACHE | |
| SCHEMBL10389958 | 0.83 | ADRB2 (0.41) | NR1H3KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL9764694 | 0.83 | NR1H3 (0.45) | NR1H3ADRB2ALDH1A1BCHE | |
| SCHEMBL9764542 | 0.83 | ADRB2 (0.41) | NR1H3ADRB2ALDH1A1SLC2A1 | |
| SCHEMBL9764329 | 0.83 | ADRB2 (0.39) | NR1H3ADRB2SLC2A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |