Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9549925 | 0.92 | MEN1 (0.41) | OPRM1OPRD1OPRK1OPRL1MTNR1A | |
| Fumaric Acid SCHEMBL9549905 | 0.92 | MEN1 (0.41) | OPRM1OPRD1OPRK1OPRL1MTNR1A | |
| SCHEMBL9550005 | 0.79 | FDFT1 (0.37) | — | |
| Fumaric Acid SCHEMBL9764009 | 0.78 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| Fumaric Acid SCHEMBL9764004 | 0.78 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL9549926 | 0.77 | SIGMAR1 (0.47) | — | |
| SCHEMBL9550050 | 0.76 | HTR1A (0.44) | HTR1ASLC6A4 | |
| SCHEMBL9550040 | 0.73 | OPRK1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL9549934 | 0.70 | BCHE (0.42) | — | |
| SCHEMBL9550070 | 0.65 | HTR7 (0.35) | OPRM1OPRD1OPRK1OPRL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010083-A | Cognition activator; Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1991-04-23 | — | — | US | claimed |