Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764833 | 0.88 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9764809 | 0.82 | PLA2G10 (0.40) | PLA2G10PLA2G2AALOX5SLCO1B1HNF4A | |
| SCHEMBL10559630 | 0.81 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9764866 | 0.81 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9764883 | 0.79 | ALOX5 (0.39) | PLA2G10PLA2G2AALOX5SLCO1B1 | |
| SCHEMBL9764825 | 0.77 | SLC9A1 (0.33) | ALOX5 | |
| SCHEMBL10561140 | 0.76 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9373618 | 0.76 | ALOX5 (0.57) | ALOX5 | |
| Ammonia Solution, Strong SCHEMBL9764837 | 0.74 | ALDH1A1 (0.39) | ALOX5 | |
| SCHEMBL9764870 | 0.73 | ALDH1A1 (0.38) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422079-A4 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0422079-A1 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | ABBOTT LABORATORIES (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989012636-A1 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | ABBOTT LABORATORIES (US) | 1989-12-28 | — | — | WO | disclosed |