Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764883 | 0.83 | ALOX5 (0.39) | SLC9A1ALOX5DYRK1A | |
| SCHEMBL9764833 | 0.83 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9764852 | 0.77 | PLA2G10 (0.40) | ALOX5 | |
| SCHEMBL10559630 | 0.76 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9764866 | 0.75 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9764897 | 0.74 | ALOX5 (0.48) | ALOX5DYRK1A | |
| SCHEMBL9764814 | 0.73 | ALOX5 (0.45) | SLC9A1ALOX5 | |
| SCHEMBL10556067 | 0.72 | ALOX5 (0.45) | ALOX5 | |
| Ammonia Solution, Strong SCHEMBL9764837 | 0.69 | ALDH1A1 (0.39) | ALOX5 | |
| SCHEMBL9764922 | 0.69 | ALOX5 (0.49) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422079-A4 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0422079-A1 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | ABBOTT LABORATORIES (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1989012636-A1 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | ABBOTT LABORATORIES (US) | 1989-12-28 | — | — | WO | disclosed |