Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765441 | 0.71 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL8561841 | 0.70 | PTGS1 (0.31) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9031233 | 0.69 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9014691 | 0.67 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6847079 | 0.66 | RAB9A (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7085122 | 0.65 | GRM5 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9006898 | 0.64 | RARA (0.31) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4523627 | 0.64 | CYP1A2 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6494578 | 0.63 | CYP11B1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9024091 | 0.63 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053523-A | Chemical intermediate for compounds having retinoic acid-like activity | ALLERGAN, INC. (US) | 1991-10-01 | — | — | US | disclosed |