Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765224 | 0.84 | ALDH1A1 (0.53) | KDM4EMAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9765242 | 0.69 | MAPT (0.66) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL25575759 | 0.69 | CRBN (0.49) | KDM4EMAPTALDH1A1L3MBTL1POLB | |
| SCHEMBL144438 | 0.69 | KDM4E (0.53) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL486125 | 0.68 | MAPT (0.73) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11036136 | 0.67 | KDM4E (0.43) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5528033 | 0.67 | ALDH1A1 (0.62) | KDM4EMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL805356 | 0.66 | MAPT (0.61) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10951870 | 0.66 | ALKBH5 (0.49) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL23271829 | 0.66 | KDM4E (0.50) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260562-B1 | ASYMMETRIC 1:2 CHROMIUM COMPLEX DYESTUFFS | BAYER AG (DE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0260562-A2 | Asymmetric 1:2 chromium complex dyestuffs | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |