Styrene

Styrene

SCHEMBL9765284

C=C(CCCC)c1ccccc1.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=Cc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.46
CES1 P23141 4/20 0.46
PTGS2 P35354 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
LMNA P02545 1/20 0.39
AKT1 P31749 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
THRA P10827 2/20 0.37
THRB P10828 2/20 0.37
NAAA Q02083 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
ESR1 P03372 1/20 0.36
EGFR P00533 1/20 0.36
HDAC3 O15379 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL3803159 0.93 CES2 (0.53) CES2CES1PTGS2ALDH1A1AKT1
Styrene SCHEMBL5287077 0.93 ALDH1A1 (0.47) CES2CES1PTGS2ALDH1A1TSHR
Styrene SCHEMBL11565626 0.90 ALDH1A1 (0.44) CES2CES1PTGS2ALDH1A1TSHR
Styrene SCHEMBL987788 0.85 LMNA (0.44) CES2CES1PTGS2ALDH1A1TSHR
Styrene SCHEMBL14058497 0.84 PTGS2 (0.40) CES2CES1PTGS2ALDH1A1TSHR
SCHEMBL2376145 0.84 PTGS2 (0.41) CES2CES1PTGS2ALDH1A1TSHR
Styrene SCHEMBL27084529 0.83 ALDH1A1 (0.50) CES2CES1PTGS2ALDH1A1TSHR
SCHEMBL28429904 0.82 THRA (0.46) CES2CES1PTGS2ALDH1A1THRA
Styrene SCHEMBL8862498 0.82 LMNA (0.41) CES2CES1ALDH1A1TSHRLMNA
Styrene SCHEMBL8471452 0.82 LMNA (0.41) CES2CES1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075158-A Resin particles attached to core particles by repeated impacts from agitation; image quality, abrasion resistance KONICA CORPORATION (JP) 1991-12-24 US disclosed