Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463608 | 0.85 | MMP2 (0.62) | TBXA2RTBXAS1ALDH1A1MMP2MMP9 | |
| SCHEMBL9765276 | 0.85 | TBXA2R (0.60) | TBXA2RTBXAS1ALDH1A1POLB | |
| SCHEMBL9765248 | 0.85 | TBXA2R (0.60) | TBXA2RTBXAS1ALDH1A1POLB | |
| SCHEMBL9765251 | 0.85 | TBXA2R (0.60) | TBXA2RTBXAS1ALDH1A1POLB | |
| SCHEMBL9513663 | 0.84 | MMP2 (0.55) | TBXA2RTBXAS1ALDH1A1PIN1MMP2 | |
| SCHEMBL9765289 | 0.81 | NR3C1 (0.62) | PIN1MMP2MMP9CTSLCTSS | |
| SCHEMBL9765258 | 0.81 | ALDH1A1 (0.57) | TBXA2RTBXAS1ALDH1A1POLBTSHR | |
| SCHEMBL9472791 | 0.78 | ALDH1A1 (0.63) | TBXA2RTBXAS1ALDH1A1POLBTSHR | |
| SCHEMBL9765323 | 0.76 | TBXA2R (0.52) | TBXA2RTBXAS1ALDH1A1POLBTSHR | |
| SCHEMBL9765267 | 0.76 | ADAMTS4 (0.55) | TBXA2RTBXAS1ALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |