Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | TPI1 | P60174 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766431 | 1.00 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL4379825 | 0.83 | ALDH1A1 (0.47) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL16029572 | 0.68 | RAB9A (0.58) | KMT2AMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL19449704 | 0.66 | HCAR2 (0.59) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL4193697 | 0.66 | CASP6 (0.66) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL713717 | 0.65 | HCAR2 (0.81) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL68395 | 0.65 | HCAR2 (0.81) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL14081549 | 0.65 | HCAR2 (0.81) | KMT2AMEN1MAPTALDH1A1HPGD | |
| Methyl Alcohol SCHEMBL29035811 | 0.65 | KDM4E (0.63) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL3446064 | 0.65 | HCAR2 (0.61) | KMT2AMEN1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017577-A | Using Purine Cinnamic Acids | BURROUGHS WELLCOME CO. (US) | 1991-05-21 | — | — | US | disclosed |
| US-4981857-A | ADENOSINE ANTAGONIST | BURROUGHS WELLCOME CO. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4980379-A | ENHANCING EFFICIENCY BY REDUCING ADENOSINE LEVELS | THE UNIVERSITY OF VIRGINIA (US) | 1990-12-25 | — | — | US | disclosed |
| US-4879296-A | BLOCKING ADERNOSINE CELL SURFACE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1989-11-07 | — | — | US | disclosed |