Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766743 | 0.90 | ALDH1A1 (0.55) | ALDH1A1CYP2C19PKMGAATDP1 | |
| SCHEMBL9067423 | 0.86 | TDP1 (0.55) | ALDH1A1CYP2C19GAATDP1MEN1 | |
| SCHEMBL7621847 | 0.85 | ALDH1A1 (0.75) | ALDH1A1CYP2C19PKMGAANEK1 | |
| SCHEMBL1859291 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP2C19PKMGAANEK1 | |
| SCHEMBL9067743 | 0.83 | CA12 (0.62) | ALDH1A1CYP2C19PKMGAATDP1 | |
| SCHEMBL7624023 | 0.80 | ALDH1A1 (0.68) | ALDH1A1CYP2C19PKMGAANEK1 | |
| SCHEMBL8658900 | 0.79 | LMNA (0.52) | ALDH1A1PKMGAATDP1MEN1 | |
| SCHEMBL9067555 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TDP1KMT2ACA12CA2 | |
| Diethanolamine SCHEMBL11126581 | 0.78 | TDP1 (0.70) | ALDH1A1CYP2C19PKMGAATDP1 | |
| SCHEMBL3377119 | 0.77 | ALDH1A1 (0.66) | ALDH1A1CYP2C19PKMGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019269-A | Polymers derived from crosslinked polystyrenes and dextrans, their methods of preparation and their applications for the analysis and purification of molecules of biological origin | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1991-05-28 | — | — | US | disclosed |
| US-4950712-A | ION EXCHANGING AND AFFINITY CHROMATOGRAPHY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 1990-08-21 | — | — | US | disclosed |