SCHEMBL9767195

SCHEMBL9767195

O=C1c2ccccc2C(=O)c2c1cccc2S(=O)(=O)On1nnc2ccccc21.[NaH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 2/20 0.39
NPSR1 Q6W5P4 2/20 0.38
TSHR P16473 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
KMT2A Q03164 4/20 0.37
SIRT2 Q8IXJ6 3/20 0.37
NPC1 O15118 4/20 0.36
RAB9A P51151 3/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 4/20 0.36
APAF1 O14727 3/20 0.36
TDP2 O95551 2/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
SMAD3 P84022 1/20 0.36
HKDC1 Q2TB90 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28860543 0.77 HTT (0.61) ALDH1A1SMN1; SMN2HTTNPSR1TSHR
SCHEMBL7407286 0.77 KMT2A (0.51) SMN1; SMN2HTTNPSR1TSHRRXFP1
SCHEMBL8993708 0.76 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2HTTNPSR1TSHR
SCHEMBL2803342 0.73 SLC9A1 (0.55) ALDH1A1SMN1; SMN2NPSR1TSHRRXFP1
SCHEMBL16858648 0.72 GAA (0.50) ALDH1A1SMN1; SMN2HTTNPSR1TSHR
SCHEMBL29475407 0.72 GAA (0.50) ALDH1A1SMN1; SMN2HTTNPSR1TSHR
SCHEMBL6273531 0.72 TSHR (0.53) ALDH1A1SMN1; SMN2NPSR1TSHRRXFP1
SCHEMBL6657251 0.72 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HTTKMT2ANPC1
SCHEMBL28479855 0.70 TSHR (0.46) SMN1; SMN2NPSR1TSHRRXFP1KMT2A
SCHEMBL30516128 0.70 KCNMA1 (0.53) ALDH1A1SMN1; SMN2HTTNPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037727-A Alkali metal iodide, an alkali to provide hydroxyl ions and a stabilizer EASTMAN KODAK COMPANY (US) 1991-08-06 US disclosed
US-4965177-A USING ALKALI METAL IODIDE AS ACTIVATOR EASTMAN KODAK COMPANY (US) 1990-10-23 US disclosed