Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768037 | 0.85 | AGTR1 (0.48) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL9768033 | 0.81 | RAB9A (0.53) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL9768285 | 0.78 | AGTR1 (0.53) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL9768156 | 0.78 | AGTR1 (0.53) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL9768332 | 0.78 | AGTR1 (0.53) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL6560025 | 0.75 | KMT2A (0.66) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL9768040 | 0.72 | ALDH1A1 (0.52) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL6841567 | 0.72 | KMT2A (0.57) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL570885 | 0.70 | AGTR1 (0.54) | NPC1SMN1; SMN2RAB9AAGTR1ALDH1A1 | |
| SCHEMBL687665 | 0.70 | MAPT (0.59) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |