Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768419 | 0.92 | MAOB (0.59) | XDHPARP1MAOBBCHEACHE | |
| SCHEMBL10668875 | 0.82 | KCNA3 (0.44) | XDHBCHEACHEALK | |
| SCHEMBL9768420 | 0.81 | PARP1 (0.50) | XDHPARP1BCHEACHE | |
| SCHEMBL10338976 | 0.79 | ALDH1A1 (0.41) | XDH | |
| SCHEMBL9768415 | 0.79 | XDH (0.55) | XDHPARP1BCHEACHEALK | |
| SCHEMBL9768410 | 0.78 | ALDH1A1 (0.42) | XDHALKFGFR1 | |
| SCHEMBL1794801 | 0.77 | PARP1 (0.64) | PARP1MAOBHRH3KDR | |
| SCHEMBL9768406 | 0.77 | SMN1; SMN2 (0.52) | ALK | |
| SCHEMBL1795884 | 0.76 | PARP1 (0.66) | PARP1MAOBHRH3KDR | |
| SCHEMBL1796324 | 0.75 | PARP1 (0.61) | XDHPARP1MAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |