Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 3/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768404 | 0.92 | XDH (0.56) | MAOBPDGFRBKDRFGFR1PARP1 | |
| SCHEMBL9768406 | 0.84 | SMN1; SMN2 (0.52) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10668875 | 0.81 | KCNA3 (0.44) | BCHEACHEXDHP2RY12ALDH1A1 | |
| SCHEMBL9768420 | 0.79 | PARP1 (0.50) | MAOAPARP1BCHEACHEXDH | |
| SCHEMBL9768405 | 0.77 | L3MBTL1 (0.52) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10338976 | 0.77 | ALDH1A1 (0.41) | MAOAXDHKDM4EALDH1A1MAPT | |
| SCHEMBL9768415 | 0.77 | XDH (0.55) | PARP1BCHEACHEXDHSIGMAR1 | |
| SCHEMBL9768410 | 0.77 | ALDH1A1 (0.42) | FGFR1XDHKDM4EALDH1A1MAPT | |
| SCHEMBL21676466 | 0.77 | PARP1 (0.62) | PDGFRBKDRFGFR1MAOAPARP1 | |
| Hydrochloric Acid SCHEMBL31070034 | 0.76 | MAOA (0.69) | PDGFRBMAOAPARP1PDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |