Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768405 | 0.94 | L3MBTL1 (0.52) | SMN1; SMN2L3MBTL1MAPK1GAAPKM | |
| SCHEMBL9768419 | 0.84 | MAOB (0.59) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9768407 | 0.81 | RAD52 (0.46) | ALKHTT | |
| SCHEMBL9768425 | 0.79 | ADRB2 (0.46) | MAPT | |
| SCHEMBL9768404 | 0.77 | XDH (0.56) | ALK | |
| SCHEMBL10668875 | 0.75 | KCNA3 (0.44) | ABCB1ALDH1A1ALKLMNA | |
| SCHEMBL10338976 | 0.74 | ALDH1A1 (0.41) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9768410 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2MAPK1GAAPKMMAPT | |
| SCHEMBL9768414 | 0.72 | ADRB2 (0.47) | MAPT | |
| SCHEMBL10614432 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2L3MBTL1MAPK1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2142794-A | — | — | None | — | — | JP | disclosed |
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| JP-H02142794-A | NOVEL ENZOFUROQUINOLINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1990-05-31 | — | — | JP | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |