Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768420 | 0.90 | PARP1 (0.50) | XDHBCHEACHESIGMAR1PARP1 | |
| SCHEMBL10668875 | 0.83 | KCNA3 (0.44) | XDHALKBCHEACHE | |
| SCHEMBL10338976 | 0.82 | ALDH1A1 (0.41) | XDHPOLB | |
| SCHEMBL11769590 | 0.81 | PARP1 (0.52) | XDHALKSIGMAR1PARP1 | |
| SCHEMBL9768404 | 0.79 | XDH (0.56) | XDHALKBCHEACHEPARP1 | |
| SCHEMBL9768407 | 0.77 | RAD52 (0.46) | ALK | |
| SCHEMBL9768419 | 0.77 | MAOB (0.59) | XDHBCHEACHESIGMAR1PARP1 | |
| SCHEMBL10614432 | 0.77 | ALDH1A1 (0.45) | POLB | |
| SCHEMBL9768410 | 0.77 | ALDH1A1 (0.42) | XDHALK | |
| SCHEMBL3621488 | 0.77 | CTSV (0.60) | XDHALKSIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |