Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.33 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1133745 | 1.00 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL333821 | 0.97 | CA4 (0.46) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL5273801 | 0.97 | CA4 (0.52) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL11047081 | 0.97 | CA4 (0.46) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL11324780 | 0.97 | CA4 (0.46) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL8091375 | 0.97 | CA4 (0.52) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Water SCHEMBL6546245 | 0.97 | CA4 (0.52) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL1389538 | 0.97 | CA4 (0.50) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL15251308 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL6669346 | 0.94 | CA4 (0.48) | CA4CASP1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10982129-B2 | Composition and method for making converter-dissolver composition for dissolving metal sulfate scales from surfaces | NuGeneration Technologies, LLC (US) | 2021-04-20 | — | — | US | claimed |
| US-20180037805-A1 | Composition and Method for Making Converter-Dissolver Composition for Dissolving Metal Sulfate Scales from Surfaces | NuGeneration Technologies, LLC dba NuGenTec (US) | 2018-02-08 | — | — | US | claimed |
| WO-2018026436-A1 | COMPOSITION AND METHOD FOR MAKING CONVERTER-DISSOLVER COMPOSITION FOR DISSOLVING METAL SULFATE SCALES FROM SURFACES | NuGeneration Technologies, LLC (US) | 2018-02-08 | — | — | WO | claimed |
| US-8586012-B2 | Body wash with sunscreen system and method | Solise LLC (US) | 2013-11-19 | — | — | US | claimed |
| US-20110020253-A1 | BODY WASH WITH SUNSCREEN SYSTEM AND METHOD | ARIZONA SUNWASH, LLC (US) | 2011-01-27 | — | — | US | claimed |
| EP-3694479-B1 | A METHOD OF TREATING HAIR OR SKIN WITH A PERSONAL CARE COMPOSITION IN A FOAM FORM | PROCTER & GAMBLE (US) | 2026-01-14 | — | — | EP | disclosed |
| US-12394827-B2 | Binder composition for non-aqueous secondary battery heat-resistant layer, slurry composition for non-aqueous secondary battery heat-resistant layer, heat-resistant layer for non-aqueous secondary battery, and non-aqueous secondary battery | ZEON CORPORATION (JP) | 2025-08-19 | — | — | US | disclosed |
| EP-4583709-A1 | AQUEOUS ANTIMICROBIAL COMPOSITION | Dow Global Technologies LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| US-20250197677-A1 | Two-Part Curable Adhesive Composition | HENKEL AG & CO KGAA (DE) | 2025-06-19 | — | — | US | disclosed |
| WO-2025127084-A1 | RUBBER COMPOSITION AND METHOD FOR USING POLYPHENYLENE ETHER | 旭化成株式会社 | 2025-06-19 | — | — | WO | disclosed |
| WO-2025028649-A1 | BINDER FOR LITHIUM-ION BATTERY POSITIVE ELECTRODE, SLURRY FOR FORMING LITHIUM-ION BATTERY POSITIVE ELECTRODE MIXTURE LAYER, POSITIVE ELECTRODE FOR LITHIUM-ION BATTERY, AND LITHIUM-ION BATTERY | 東ソー株式会社 | 2025-02-06 | — | — | WO | disclosed |
| WO-2024241539-A1 | AEROSOL-TYPE CREAM HAIR DYE COMPOSITION | 株式会社ダリヤ | 2024-11-28 | — | — | WO | disclosed |
| EP-1488789-A1 | EYE DROPS CONTAINING TETRAZOLE DERIVATIVE | Sankyo Company, Limited (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1454617-A1 | HAIR DYE COMPOSITION | Kao Corporation (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-6531508-B1 | Penem antibiotic | SUNTORY LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| EP-1142573-A1 | ANTIBACTERIAL MEDICINAL COMPOSITIONS | SUNTORY LIMITED (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-5786317-A | MIXTURE OF ALKALI METAL SILICATE, ALCOHOL, SEQUESTERING AGENT, SURFACTANT, SODIUM BISULFITE REDUCING AGENT AND WATER | TOWNSEND CLINT E (US) | 1998-07-28 | — | — | US | disclosed |
| US-5229270-A | Quantitative analysis for chloride by forming a chelate with calcium ion, deactivated alpha-amylase, a calcium chelate and an activity measuring substance | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0275398-B1 | REAGENT FOR THE DETERMINATION OF CHLORIDE IONS | Kanto Kagaku Kabushiki Kaisha (JP) | 1992-08-05 | — | — | EP | disclosed |
| EP-0275398-A2 | Reagent for the determination of chloride ions | Kanto Kagaku Kabushiki Kaisha (JP) | 1988-07-27 | — | — | EP | disclosed |