Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 5/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1133745 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| Water SCHEMBL976875 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL9656600 | 0.97 | CA4 (0.55) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL11344222 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL8984838 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL15251308 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL6669346 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL865415 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL4705339 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM | |
| SCHEMBL6670067 | 0.97 | CA4 (0.48) | CA4CASP1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083875-A | Solid glyphosate formulations | MONSANTO COMPANY (US) | 2000-07-04 | — | — | US | claimed |
| US-4994376-A | Using N-carbobenzoxy-glycyl-glycyl-arginine-B-naphthylamide | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NY (US) | 1991-02-19 | — | — | US | claimed |
| US-20220315801-A1 | POLISHING COMPOSITION AND METHOD FOR SELECTIVELY REMOVING SILICON NITRIDE | FUJIMI INCORPORATED (JP) | 2022-10-06 | — | — | US | disclosed |
| US-11116786-B2 | Combination of glycosaminoglycans and an antacid agent and compositions thereof | APHARM S.R.L. (IT) | 2021-09-14 | — | — | US | disclosed |
| US-10815387-B2 | Aqueous ink jet ink composition, ink jet recording method, and ink jet recording apparatus | SEIKO EPSON CORPORATION (JP) | 2020-10-27 | — | — | US | disclosed |
| CN-109181671-B | Mobility control polymers for enhanced oil recovery | 艺康美国股份有限公司 | 2020-08-25 | — | — | CN | disclosed |
| EP-3461650-B1 | RECORDING METHOD | SEIKO EPSON CORP (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-10723903-B2 | Ink set and recording method | SEIKO EPSON CORPORATION (JP) | 2020-07-28 | — | — | US | disclosed |
| US-10696860-B2 | Reaction liquid and recording method | SIEKO EPSON CORPORATION (JP) | 2020-06-30 | — | — | US | disclosed |
| EP-3461866-B1 | INK SET AND RECORDING METHOD | SEIKO EPSON CORP (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-10669441-B2 | Aqueous ink jet ink composition and ink jet recording method | SEIKO EPSON CORPORATION (JP) | 2020-06-02 | — | — | US | disclosed |
| US-4393007-A | ONE STEP PRODUCTION OF ANTHRAQUINONE DYES FROM 1-NITRO-ANTHRAQUINONE | CIBA-GEIGY AG (CH) | 1983-07-12 | — | — | US | disclosed |
| EP-0070656-A2 | Immobilized superoxide dismutase, its production and pharmaceutical composition | Takeda Chemical Industries, Ltd. (JP) | 1983-01-26 | — | — | EP | disclosed |
| US-4342665-A | COMPRISING A SURFACTANT, A CONJUGATED DIENE-MALEIC ACID OR DERIVATIVE COPOLYMER, CALCIUM ION AND WATER | NIPPON OIL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| EP-0045222-A2 | Mn-Superoxide dismutase, its production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-02-03 | — | — | EP | disclosed |
| US-4223009-A | A TERTIARY AMINO ALKYL ESTER OF ACRYLIC OR METHACRYLIC ACID AS COMONOMER | GAF CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4165367-A | WITH DIALKYLAMINOALKYL ACRYLATE OR METHACRYLATE | GAF CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0001567-A1 | Thienamycin related antibiotics PS-6 and PS-7, process for their production and compositions containing them | SANRAKU-OCEAN CO., LTD. (JP) | 1979-05-02 | — | — | EP | disclosed |
| US-4152515-A | PHOSPHOROUS-FREE | LEVER BROTHERS COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-3960679-A | Process for hydrodimerizing olefinic compounds | MONSANTO COMPANY (US) | 1976-06-01 | — | — | US | disclosed |