Water

Water

SCHEMBL976877

NC(CC(=O)[O-])C(CC(=O)[O-])(CC(=O)[O-])NCC(=O)[O-].O.O.O.O.[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CA4 P22748 2/20 0.31
CPT2 P23786 1/20 0.31
CPT1A P50416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11495893 1.00 CA2 (0.32) CA2CA4CPT2CPT1A
Water SCHEMBL9243946 1.00 CA2 (0.32) CA2CA4CPT2CPT1A
Water SCHEMBL8030606 0.98 CA4 (0.34) CA2CA4CPT2CPT1A
Water SCHEMBL8963366 0.98 CA4 (0.34) CA2CA4CPT2CPT1A
Water SCHEMBL2170087 0.98 CA2 (0.31) CA2CA4CPT2CPT1A
SCHEMBL1389543 0.98 CA2 (0.33) CA2CA4CPT2CPT1A
Water SCHEMBL11136198 0.97 CPT2 (0.31) CPT2CPT1A
SCHEMBL509934 0.97 CA2 (0.32) CA2CA4CPT2CPT1A
SCHEMBL7149875 0.97 CA4 (0.35) CA2CA4CPT2CPT1A
SCHEMBL11099372 0.97 CA2 (0.32) CA2CA4CPT2CPT1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341083-B1 STABILIZED REDISPERSIBLE POLYMER POWDER COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-08 EP disclosed
EP-2341084-B1 Redispersible polymer powders stabilized with protective colloid compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-25 EP disclosed
US-20140086858-A1 BODY WASH WITH SUNSCREEN SYSTEM AND METHOD Solise LLC (US) 2014-03-27 US disclosed
US-8586012-B2 Body wash with sunscreen system and method Solise LLC (US) 2013-11-19 US disclosed
EP-2341084-A1 Redispersible polymer powders stabilized with protective colloid compositions DOW Chemical Company (US) 2011-07-06 EP disclosed
EP-2341083-A1 Stabilized redispersible polymer powder compositions DOW Chemical Company (US) 2011-07-06 EP disclosed
US-20110020253-A1 BODY WASH WITH SUNSCREEN SYSTEM AND METHOD ARIZONA SUNWASH, LLC (US) 2011-01-27 US disclosed