Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770632 | 0.77 | KDM4E (0.44) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL9770495 | 0.77 | KDM4E (0.44) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL9770657 | 0.71 | KDM4E (0.49) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL9770631 | 0.68 | GAA (0.46) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL9770499 | 0.68 | KDM4E (0.45) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL9770550 | 0.65 | LMNA (0.46) | ALDH1A1GAAKDM4ELMNAMAPK1 | |
| SCHEMBL16237146 | 0.64 | ALDH1A1 (0.57) | ALDH1A1GAALMNASMN1; SMN2MAPT | |
| SCHEMBL9770654 | 0.62 | KDM4E (0.56) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL29262987 | 0.62 | ALDH1A1 (0.54) | ALDH1A1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL189298 | 0.61 | KDM4E (0.72) | CFTRPIK3CAALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |