Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770534 | 0.84 | LMNA (0.47) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL9770634 | 0.81 | LMNA (0.53) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL9770566 | 0.80 | KDM4E (0.55) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL9770553 | 0.76 | LMNA (0.51) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL9770626 | 0.72 | KDM4E (0.51) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL11915878 | 0.72 | KDM4E (0.49) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL9770550 | 0.72 | LMNA (0.46) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL28188086 | 0.71 | ABCG2 (0.49) | ALDH1A1MAPTMAPK1KDM4EHTT | |
| SCHEMBL9770640 | 0.71 | CTSB (0.54) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL1825303 | 0.68 | LMNA (0.97) | ALDH1A1MAPTLMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019574-A | 3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0361489-A2 | Novel 3,4-diaminoquinoline and pyridine compounds | Chugai Seiyaku Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | disclosed |