Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770576 | 0.81 | GAA (0.58) | ALDH1A1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL8764222 | 0.79 | MGLL (0.52) | PLA2G7TSHRMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL7337661 | 0.78 | GSK3A (0.57) | ALOX12ALDH1A1PLA2G7TSHRMAPK1 | |
| SCHEMBL9770647 | 0.76 | RAB9A (0.66) | ALDH1A1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL9770595 | 0.75 | PARL (0.47) | ALDH1A1PARLLMNA | |
| SCHEMBL8469734 | 0.74 | POLB (0.51) | ALOX12ALDH1A1TSHRRAB9APOLB | |
| SCHEMBL11114870 | 0.74 | L3MBTL1 (0.60) | ALDH1A1TSHRMAPK1MAPTMEN1 | |
| SCHEMBL15105715 | 0.74 | ALOX12 (0.45) | ALOX12ALDH1A1GFERPLA2G7RAB9A | |
| SCHEMBL20248861 | 0.73 | ALOX12 (0.70) | ALOX12ALDH1A1GFERPLA2G7MAPK1 | |
| SCHEMBL21371330 | 0.72 | TSHR (0.44) | ALOX12ALDH1A1PLA2G7TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |