Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583437 | 0.89 | CES1 (0.57) | CES1SMN1; SMN2MAPTL3MBTL1PTPN1 | |
| SCHEMBL9565947 | 0.87 | CES1 (0.55) | CES1SMN1; SMN2MAPTL3MBTL1PTPN1 | |
| SCHEMBL9655468 | 0.87 | CES1 (0.55) | CES1SMN1; SMN2MAPTPTPN1GSK3B | |
| SCHEMBL9630805 | 0.87 | CES1 (0.55) | CES1SMN1; SMN2MAPTPTPN1GSK3B | |
| SCHEMBL711848 | 0.80 | PLOD2 (0.50) | CES1PTPN1RAB9ANPC1 | |
| SCHEMBL583454 | 0.79 | CES1 (0.43) | CES1MAPTGSK3BLMNAHPGD | |
| SCHEMBL584064 | 0.79 | CES2 (0.43) | CES1MAPTL3MBTL1GSK3BRAB9A | |
| SCHEMBL9770781 | 0.79 | CA2 (0.55) | CES1SMN1; SMN2MAPTPTPN1GSK3B | |
| SCHEMBL4502846 | 0.77 | CES1 (0.75) | CES1SMN1; SMN2MAPTL3MBTL1PTPN1 | |
| SCHEMBL713840 | 0.77 | CES2 (0.50) | CES1SMN1; SMN2MAPTPTPN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289390-B1 | PROCESS FOR ELIMINATING RADIOACTIVITY FROM EFFLUENTS BY LIQUID-LIQUID EXTRACTION | RHONE-POULENC CHIMIE (FR) | 1991-10-16 | — | — | EP | disclosed |
| US-5006254-A | Extraction with halogenated beta-diketone | RHONE-POULENC CHIMIE (FR) | 1991-04-09 | — | — | US | disclosed |