SCHEMBL584064

SCHEMBL584064

O=C(CF)C(F)(F)C(=O)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.43
CES1 P23141 3/20 0.43
GSK3B P49841 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
GABRB1 P18505 1/20 0.40
GABRB2 P47870 1/20 0.40
SRD5A2 P31213 1/20 0.38
MAPK1 P28482 1/20 0.38
ERCC5 P28715 1/20 0.38
FEN1 P39748 1/20 0.38
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711848 0.83 PLOD2 (0.50) CES2CES1CA1CA2RAB9A
SCHEMBL583454 0.81 CES1 (0.43) CES2CES1GSK3BLMNAMAPT
SCHEMBL9770781 0.81 CA2 (0.55) CES2CES1GSK3BALDH1A1LMNA
SCHEMBL583437 0.81 CES1 (0.57) CES2CES1GSK3BALOX15TSHR
SCHEMBL9565947 0.79 CES1 (0.55) CES2CES1GSK3BALOX15TSHR
SCHEMBL9655468 0.79 CES1 (0.55) CES2CES1GSK3BALOX15TSHR
SCHEMBL9630805 0.79 CES1 (0.55) CES2CES1GSK3BALOX15TSHR
SCHEMBL9770874 0.79 ALDH1A1 (0.48) ALDH1A1LMNAGAACYP1A2CYP2C19
SCHEMBL9770760 0.79 CES1 (0.46) CES1GSK3BALDH1A1LMNAMAPT
SCHEMBL29137350 0.78 CES1 (0.52) CES2CES1GSK3BALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417216-A2 MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION Inbio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz Gbr (DE) 2012-02-15 EP disclosed
EP-1848786-B1 ELECTROLUMINESCENT MATERIALS AND DEVICES MERCK PATENT GMBH (DE) 2011-02-02 EP disclosed
WO-2010115503-A2 MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION INBIO PROF. JÜRGEN BÜDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ GBR (DE) 2010-10-14 WO disclosed
US-7811676-B2 Electroluminescent materials and devices MERCK PATENT GMBH (DE) 2010-10-12 US disclosed
US-7767315-B2 Incorporating a fluorescent organometallic complex in the toner or in the paper in which the fluorescent dye gives off light with a characteristic spectrum when exposed to ultraviolet light; authenticated at room temperature; strong emission which can be digitized; paper, cloth, and plastic MERCK PATENT GMBH (DE) 2010-08-03 US disclosed
US-20100038632-A1 ELECTROLUMINESCENT DEVICE OLED-T LIMITED (GB) 2010-02-18 US disclosed
US-20090167158-A1 Electroluminescent Devices MERCK PATENT GMBH (DE) 2009-07-02 US disclosed
EP-2044170-A1 ELECTROLUMINESCENT DEVICE Merck Patent GmbH (DE) 2009-04-08 EP disclosed
US-20090009062-A1 Electroluminescent Devices MERCK PATENT GMBH (DE) 2009-01-08 US disclosed
US-20080265210-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2008-10-30 US disclosed
WO-2002102924-A2 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-12-27 WO disclosed
WO-2002091493-A2 ELECTROLUMINESCENT DEVICE ELAM-T LIMITED (GB) 2002-11-14 WO disclosed
WO-2002090465-A1 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-11-14 WO disclosed
WO-2002090466-A1 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-11-14 WO disclosed
WO-2002087283-A1 ELECTROLUMINESCENT DEVICES INCORPORATING MIXED METAL ORGANIC COMPLEXES ELAM-T LIMITED (GB) 2002-10-31 WO disclosed
WO-2002086015-A2 MIXED METAL ORGANIC COMPLEXES ELAM-T LIMITED (GB) 2002-10-31 WO disclosed
WO-2002075820-A1 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-09-26 WO disclosed
WO-2002043447-A2 ELECTROLUMINESCENT DEVICE ELAM-T LIMITED (GB) 2002-05-30 WO disclosed
WO-2002043446-A1 ELECTROLUMINESCENT DEVICE ELAM-T LIMIED (GB) 2002-05-30 WO disclosed
WO-2002043444-A2 ELECTROLUMINESCENT DEVICE ELAM-T LIMITED (GB) 2002-05-30 WO disclosed