Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711848 | 0.83 | PLOD2 (0.50) | CES1CES2CA1CA2MLYCD | |
| SCHEMBL9770781 | 0.81 | CA2 (0.55) | CES1CES2GSK3BCA2HDAC1 | |
| SCHEMBL584064 | 0.81 | CES2 (0.43) | CES1CES2GSK3BCA1CA2 | |
| SCHEMBL583437 | 0.81 | CES1 (0.57) | CES1CES2GSK3BLMNAMAPT | |
| SCHEMBL29137293 | 0.80 | CES1 (0.54) | CES1CES2GSK3BOGG1CA1 | |
| SCHEMBL9565947 | 0.79 | CES1 (0.55) | CES1CES2GSK3BLMNAMAPT | |
| SCHEMBL9630805 | 0.79 | CES1 (0.55) | CES1CES2GSK3BLMNAMAPT | |
| SCHEMBL9655468 | 0.79 | CES1 (0.55) | CES1CES2GSK3BLMNAMAPT | |
| SCHEMBL9770760 | 0.79 | CES1 (0.46) | CES1GSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL9770874 | 0.79 | ALDH1A1 (0.48) | HDAC4HDAC6LMNATDP1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417216-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | Inbio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz Gbr (DE) | 2012-02-15 | — | — | EP | claimed |
| WO-2010115503-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | INBIO PROF. JÜRGEN BÜDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ GBR (DE) | 2010-10-14 | — | — | WO | claimed |
| US-20120107624-A1 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | INBIO PROF. JURGEN BUDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2417216-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | Inbio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz Gbr (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115503-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | INBIO PROF. JÜRGEN BÜDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ GBR (DE) | 2010-10-14 | — | — | WO | disclosed |
| EP-1086097-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER INC. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064415-A1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-12-16 | — | — | WO | disclosed |