Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | RGS4 | P49798 | 1/20 | 0.39 |
| ▸ | RGS8 | P57771 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771422 | 0.91 | EP300 (0.49) | KMT2AMAPTMEN1EP300POLB | |
| SCHEMBL9771337 | 0.87 | CMA1 (0.50) | KMT2AMEN1HDAC6EP300ALDH1A1 | |
| SCHEMBL9771342 | 0.84 | POLB (0.46) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL9826922 | 0.79 | RAB9A (0.47) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL9771335 | 0.77 | ADORA2A (0.48) | KMT2AMEN1EP300POLBALDH1A1 | |
| SCHEMBL9771405 | 0.77 | TP53 (0.53) | KMT2AMAPTMEN1HDAC6POLB | |
| SCHEMBL9827539 | 0.77 | ALDH1A1 (0.36) | KMT2AMAPTMEN1POLBALDH1A1 | |
| SCHEMBL9771318 | 0.73 | TSHR (0.33) | KMT2AALDH1A1LMNA | |
| SCHEMBL9771431 | 0.71 | TRPM8 (0.39) | KMT2AMAPTMEN1HDAC6ALDH1A1 | |
| SCHEMBL9827209 | 0.69 | POLB (0.46) | KMT2AMEN1POLBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068341-A | OPTICALLY ACTIVE HYDANTOINS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |