Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824672 | 0.81 | KMT2A (0.41) | MAPTNPC1RAB9AMITFALDH1A1 | |
| SCHEMBL4786381 | 0.79 | NPC1 (0.55) | MAPTNPC1RAB9AMITFALDH1A1 | |
| SCHEMBL2361037 | 0.70 | HTT (0.54) | MAPTNPC1RAB9AMITFALDH1A1 | |
| SCHEMBL11285030 | 0.70 | TOP2A (0.37) | NPC1RAB9AMITFPKMTOP2A | |
| SCHEMBL27691970 | 0.69 | HTT (0.42) | MAPTNPC1RAB9AMITFALDH1A1 | |
| SCHEMBL27692058 | 0.69 | PKM (0.41) | ALDH1A1PKMTOP2A | |
| SCHEMBL4782675 | 0.68 | TBXAS1 (0.39) | MAPTNPC1RAB9AMITFALDH1A1 | |
| SCHEMBL2323909 | 0.68 | GAA (0.41) | MAPTNPC1RAB9AMITFALDH1A1 | |
| SCHEMBL13861649 | 0.67 | NPC1 (0.59) | NPC1RAB9AMITFALDH1A1SMN1; SMN2 | |
| SCHEMBL9775182 | 0.66 | PLA2G1B (0.38) | MAPTNPC1RAB9AMITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026850-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-25 | — | — | US | disclosed |