Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173533 | 0.76 | CYP3A4 (0.48) | CYP3A4HPGDCRHBPCRHR2HSD17B10 | |
| SCHEMBL9775380 | 0.74 | CA1 (0.40) | CYP3A4HPGDCRHBPCRHR2HSD17B10 | |
| SCHEMBL6849517 | 0.69 | LMNA (0.37) | POLBGRM2 | |
| SCHEMBL8060796 | 0.66 | HSD17B10 (0.65) | CYP3A4HPGDCRHBPCRHR2HSD17B10 | |
| SCHEMBL1002836 | 0.65 | ALDH1A1 (0.43) | CYP3A4HPGDHSD17B10POLBAKR1C4 | |
| SCHEMBL9623395 | 0.63 | ABL1 (0.50) | CYP3A4HPGDCRHBPCRHR2HSD17B10 | |
| SCHEMBL8084711 | 0.63 | RXRA (0.58) | HSD17B10HCAR1TSHR | |
| SCHEMBL2474256 | 0.62 | CYP3A4 (0.56) | CYP3A4HPGDHSD17B10POLBTSHR | |
| SCHEMBL11046174 | 0.62 | CYP3A4 (0.52) | CYP3A4HPGDCRHBPCRHR2HSD17B10 | |
| SCHEMBL9775407 | 0.62 | CA1 (0.44) | HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373690-A2 | Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-20 | — | — | EP | claimed |
| US-5049644-A | Self-extinguishing | ENICHEM TECNORESINE S.P.A. (IT) | 1991-09-17 | — | — | US | disclosed |
| EP-0373690-A2 | Flame-resistant polycarbonates containing units deriving from halogenated triphenolbenzamido compounds in their polymer chain | ENICHEM S.p.A. (IT) | 1990-06-20 | — | — | EP | disclosed |