Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.72 |
| ▸ | MMP1 | P03956 | 4/20 | 0.69 |
| ▸ | MMP12 | P39900 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 5/20 | 0.63 |
| ▸ | MMP9 | P14780 | 5/20 | 0.63 |
| ▸ | MMP13 | P45452 | 3/20 | 0.63 |
| ▸ | MMP3 | P08254 | 2/20 | 0.63 |
| ▸ | MMP7 | P09237 | 2/20 | 0.63 |
| ▸ | MMP14 | P50281 | 2/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.63 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.63 |
| ▸ | MMP8 | P22894 | 2/20 | 0.63 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899544 | 0.90 | KAT6A (0.58) | KAT6AMMP1MMP12GAAMMP2 | |
| SCHEMBL9777953 | 0.83 | MEP1B (0.61) | KAT6AMMP1MMP12GAAMEP1B | |
| SCHEMBL5899468 | 0.82 | MEN1 (0.67) | KAT6AMMP1MMP12GAASMN1; SMN2 | |
| SCHEMBL23014260 | 0.82 | KAT6A (0.52) | KAT6AMMP1MMP12GAAMEP1B | |
| SCHEMBL10890150 | 0.81 | MMP1 (1.00) | KAT6AMMP1MMP12GAAMMP2 | |
| SCHEMBL6271017 | 0.81 | MMP1 (0.80) | KAT6AMMP1MMP12GAAMMP2 | |
| SCHEMBL9777957 | 0.81 | ALDH1A1 (0.64) | KAT6AMMP1MMP12GAAMAPT | |
| SCHEMBL5899462 | 0.80 | KAT6A (0.71) | KAT6AMMP1MMP12GAASMN1; SMN2 | |
| SCHEMBL5899482 | 0.79 | L3MBTL1 (0.60) | KAT6AMMP1MMP12GAAMMP2 | |
| SCHEMBL5899737 | 0.79 | MMP1 (0.63) | KAT6AMMP1MMP12GAAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | KAT6A 2440/4885MMP1 369/4885MMP12 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.