Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 12/20 | 0.56 |
| ▸ | MMP2 | P08253 | 10/20 | 0.56 |
| ▸ | MMP14 | P50281 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983944 | 0.86 | HTR6 (0.54) | MMP9MMP2HTTSMN1; SMN2NR3C1 | |
| SCHEMBL7937431 | 0.86 | HSD11B1 (0.49) | MMP9MMP2MMP14BCHEACHE | |
| SCHEMBL9779083 | 0.86 | HTT (0.56) | MMP9MMP2MMP14HTTSMN1; SMN2 | |
| SCHEMBL6925883 | 0.85 | PTGS2 (0.60) | MMP9MMP2MMP14NR3C1MMP3 | |
| SCHEMBL5482429 | 0.85 | MMP9 (0.54) | MMP9MMP2MMP14NR3C1MMP3 | |
| SCHEMBL3310741 | 0.85 | MMP9 (0.54) | MMP9MMP2MMP14HTTNR3C1 | |
| SCHEMBL10985063 | 0.85 | ALDH1A1 (0.59) | MMP9MMP2MMP14BCHEACHE | |
| SCHEMBL7937278 | 0.85 | PKM (0.59) | MMP9MMP2MMP14MMP3MMP13 | |
| SCHEMBL10988447 | 0.85 | BCHE (0.66) | HTTSMN1; SMN2BCHEACHEFFAR4 | |
| SCHEMBL9778890 | 0.85 | HTT (0.47) | MMP9MMP2MMP14HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066409-A | Novel aryl ether sulfones | THE DOW CHEMICAL COMPANY (US) | 1991-11-19 | — | — | US | disclosed |