Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10430923 | 0.83 | GABRA1 (0.50) | ADORA2AADORA1GABRA1GABRG2GABRB3 | |
| SCHEMBL9779442 | 0.80 | F11 (0.54) | ADORA2AADORA1XDHGABRA1GABRG2 | |
| SCHEMBL31273466 | 0.76 | GABRG2 (0.67) | ADORA2AADORA1XDHGABRA1GABRG2 | |
| SCHEMBL31663506 | 0.76 | CLK4 (0.61) | ADORA2AADORA1XDHGABRA1GABRG2 | |
| SCHEMBL31663589 | 0.76 | GABRG2 (0.67) | ADORA2AADORA1XDHGABRA1GABRG2 | |
| SCHEMBL21636334 | 0.75 | ALDH1A3 (0.56) | ADORA2AADORA1GABRA1GABRG2GABRB3 | |
| SCHEMBL21636333 | 0.75 | ABCG2 (0.60) | ADORA2AADORA1GABRA1GABRG2GABRB3 | |
| SCHEMBL20632489 | 0.75 | XDH (0.51) | ADORA2AADORA1XDHF11CTSS | |
| SCHEMBL21636324 | 0.75 | GABRA1 (0.55) | ADORA2AADORA1XDHGABRA1GABRG2 | |
| SCHEMBL31663608 | 0.74 | GABRA1 (0.56) | ADORA2AADORA1XDHGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |