Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779299 | 0.88 | F11 (0.55) | F11PIN1SLC22A12XDHALDH1A1 | |
| SCHEMBL9779393 | 0.83 | ADORA3 (0.51) | F11PIN1GABRG2GABRB3GABRA5 | |
| SCHEMBL9779192 | 0.80 | ADORA2A (0.53) | F11XDHGABRA1GABRG2GABRB3 | |
| SCHEMBL10430923 | 0.80 | GABRA1 (0.50) | F11PIN1GABRA1GABRG2GABRB3 | |
| SCHEMBL10465235 | 0.79 | LRRK2 (0.46) | F11ALDH1A1POLB | |
| SCHEMBL9779491 | 0.77 | ADORA2A (0.46) | F11PIN1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL10465234 | 0.76 | ALDH1A1 (0.38) | F11PIN1ALDH1A1POLB | |
| SCHEMBL9874282 | 0.76 | MAPT (0.55) | PDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8878224 | 0.76 | MAPT (0.51) | ADORA2AADORA1ALDH1A1 | |
| SCHEMBL9779236 | 0.76 | ALDH1A1 (0.48) | F11PIN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |