Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779442 | 0.88 | F11 (0.54) | F11PIN1SLC22A12XDHALDH1A1 | |
| SCHEMBL9779485 | 0.82 | ADORA3 (0.51) | F11PIN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4509671 | 0.80 | FABP3 (0.51) | PIN1GRM5ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9779236 | 0.77 | ALDH1A1 (0.48) | F11PIN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL31663605 | 0.76 | CLK4 (0.47) | F11PIN1GRM5ABCG2 | |
| SCHEMBL5557535 | 0.76 | CLK4 (0.47) | F11PIN1GRM5ABCG2 | |
| SCHEMBL4775928 | 0.76 | F11 (0.54) | F11PIN1SLC22A12XDHGRM5 | |
| SCHEMBL7076894 | 0.75 | F11 (0.51) | F11PIN1SLC22A12XDHGRM5 | |
| SCHEMBL9779267 | 0.74 | CD274 (0.52) | ALDH1A1HPGD | |
| SCHEMBL9779393 | 0.73 | ADORA3 (0.51) | F11PIN1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037824-A | Cardiotonic, antiischemic agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0387070-A2 | N-Containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |