Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RGS4 | P49798 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779995 | 0.84 | MEN1 (0.39) | ALOX5MAPTLMNAMGLLHTT | |
| SCHEMBL9779986 | 0.84 | G6PD (0.47) | ALOX5GSK3AGSK3B | |
| SCHEMBL9780043 | 0.81 | ALDH1A1 (0.42) | MAPTLMNACTSGCMA1HTT | |
| SCHEMBL9780007 | 0.81 | POLB (0.49) | MAPTLMNAMGLLHTTSMN1; SMN2 | |
| SCHEMBL9780008 | 0.80 | ALOX5 (0.55) | ALOX5MAPTLMNAMGLLADRB1 | |
| SCHEMBL9779997 | 0.77 | BPTF (0.38) | ALOX5MMP2POLB | |
| SCHEMBL9780037 | 0.74 | ALOX5 (0.46) | ALOX5MAPTPOLB | |
| SCHEMBL9779956 | 0.73 | ALOX5 (0.53) | ALOX5MAPTMGLLHTTADRB1 | |
| SCHEMBL9779943 | 0.73 | NPC1 (0.49) | ALOX5LMNASMN1; SMN2MMP2NPC1 | |
| SCHEMBL9780035 | 0.72 | ALOX5 (0.53) | ALOX5MAPTELANEMGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |